I alternate Vitality capsules with pure Senna (Neo-Lax) and Cape Aloe for regularity. I take 2 vitality capsules at night. They work well, although I was using Neo-Lax which contains more Senna for so long, that it evacuates me better. I like to alternate products and hopefully one day the vitality capsules alone will work better for me. Vitality also has some Senna leaf powder in them.