I have arthritis so bad in my right knee that most nights I cannot sleep because the pain is so bad. I have tried so many ointments, creams, patches, sleeves, just about everything you can buy to relieve the pain. I decided to try the tapes and I couldn't tell much difference the first couple of days of using it but after the third day, I began to feel less pain. I am now on my 2nd week and the tapes have helped better than anything I've tried.