I suffer with arthritis in the knee, a minis is tear and bakers cyst all in the same knee, I had a couple of patches that would not stick but I have been using them for about 3 weeks now and not had problems since, the pain eases as soon as you put them on, you get a slight burning sensation at first but this subsided after a few minutes, the swelling has gone down by about 25% and I can walk a lot better now.